Provides viewers with an inside look at baseball's greatest treasures and also explore the big busines of the baseball memorabilia industry.

Traces the life of Lou Gehrig, famous baseball Hall of Fame player who played in 2130 consecutive games before falling at age 37 to ALS, a deadly nerve disease which now bears his name. Gehrig is followed from his athletic childhood in New York to his famous 'Luckiest Man' speech at his farewell day in 1939.